Clinical Efficacy of Sublingual Immunotherapy with Japanese Cedar Pollen During the Cypress Pollen Season

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Changes of micro-RNAs in asymptomatic subjects sensitized to Japanese cedar pollen after prophylactic sublingual immunotherapy

Japanese cedar pollinosis is the predominant seasonal allergic rhinitis in Japan, and it has increased in prevalence during the past 10 years. Sublingual immunotherapy (SLIT) is considered a safe and effective treatment for pollinosis. Micro-RNAs (miRNAs) are a class of short single-stranded RNA molecules that posttranscriptionally silence gene expression and may mediate allergic immune respons...

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Two thirds of forest walkers with Japanese cedar pollinosis visit forests even during the pollen season.

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Prophylactic Sublingual Immunotherapy for Japanese Cedar Pollinosis

Sublingual immunotherapy is much safer than conventional percutaneous immunotherapy. This is the only treatment available which can completely cure the disease. A randomized, placebocontrolled, double-blind study has revealed that sublingual immunotherapy is both effective and safe for the patient with this pollinosis [3]. Only recently, standardized Japanese cedar pollen extract became availab...

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Clinical efficacy and safety of sublingual immunotherapy with tree pollen extract in children.

BACKGROUND Subcutaneous immunotherapy has been the principal approach of immunotherapy in the treatment of allergic diseases. Several clinical studies with birch, alder or hazel pollen extract conducted as subcutaneous immunotherapy have been published suggesting a well-tolerated and clinically effective treatment. Only a few clinical studies of sublingual immunotherapy (SLIT) with these allerg...

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Histamine antagonist Bepotastine suppresses nasal symptoms caused by Japanese cedar and cypress pollen exposure

Objective: To determine the efficacy of the antihistamine bepotastine on treating nasal symptoms in patients with Japanese cedar and cypress pollinosis, based on two previous studies that looked at bepotastine OD's inhibitory effect on symptom onset after exposure. Design and methods: Randomized double-blind placebo controlled, parallel study. Twenty-eight volunteers with Japanese cedar and cyp...

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ژورنال

عنوان ژورنال: Nippon Jibiinkoka Gakkai Kaiho

سال: 2017

ISSN: 0030-6622,1883-0854

DOI: 10.3950/jibiinkoka.120.833